Table 4.

Univariate analysis of SVZ-dosimetric data prognostic factors (low dose vs high dose) for time-to-progression (TTP) and overall survival (OS) using various thresholds

	Without temporal horn (TH-)					With temporal horn (TH+)
	n =	Med TTP (mo)	p	Med OS (mo)	p	n =	Med TTP (mo)	p	Med OS (mo)	p
Dmean (40 Gy)
iSVZ
≤ 40 Gy	15	5.2	0.283	18.9	0.549	10	5.2	0.727	20.3	0.659
> 40 Gy	25	6.6		24.7		30	5.6		24.7
bSVZ
≤ 40 Gy	30	4.6	0.023	20.7	0.198	34	5.3	0.399	24.7	0.963
> 40 Gy	10	9.4		22.7		6	9.1		11.7
Dmean (43 Gy)
iSVZ
≤ 43 Gy	17	5.3	0.529	20.3	0.392	14	12.1	0.072	26.2	0.087
> 43 Gy	23	6.4		25.1		26	4.8		20.5
bSVZ
≤ 43 Gy	33	5.3	0.073	22.7	0.397	-	-	-	-	-
> 43 Gy	7	9.1		34.2		-	-		-
V20 Gy
iSVZ
≤ 84%	15	5.3	0.528	20.7	0.709	20	-	-	-	-
> 84%	25	6.4		24.7		20	-		-
bSVZ
≤ 84%	32	5.2	0.017	22.7	0.19	39	-	-	-	-
> 84%	8	17.7		20.3		1	-		-

Abbreviations: iSVZ ipsilateral SVZ, bSVZ bilateral SVZ, VxGy volume of SVZ (%) receiving more than x Gy