Skip to main content
. 2017 Apr;187(4):884–895. doi: 10.1016/j.ajpath.2016.12.010

Figure 3.

Figure 3

Neuropathologic correlates with synaptic particle molecular markers from 40 brain autopsies. A: Values for striatum are the average of ventromedial caudate (VMC), dorsolateral caudate (DLC), and putamen. Percentage particles +Aβ42 in striatum and middle frontal gyrus (MFG) stratified by National Institute on Aging - Alzheimer's Association (NIA-AA) A score for Aβ42 deposition. Two-way analysis of variance shows P < 0.0001 for A score and brain region, and P < 0.05 for interaction. Corrected multiple paired comparisons for regions show significance for A score 2 or 3 versus A score 1. B: MFG percentage particles +PHF-tau stratified by NIA-AA B score for neurofibrillary degeneration. One-way analysis of variance shows P < 0.01; corrected multiple paired comparisons show significance for B score 3 versus B score 1 (and also versus B score 2). C: Percentage particles +DAT in three regions of Hu striatum stratified by + Lewy body disease (+LBD) or −LBD. Two-way analysis of variance is significant only for LBD (P < 0.0001); corrected multiple paired comparisons for region show significance for LBD+ versus −LBD in each region. ∗∗P < 0.01, ∗∗∗P < 0.001.