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. 2017 Apr;187(4):884–895. doi: 10.1016/j.ajpath.2016.12.010

Figure 4.

Figure 4

Clinicopathologic correlates with synaptic particle molecular markers from 40 Hu brain autopsies. A: The percentage particles +DAT varies significantly by clinicopathologic group (P < 0.001) but not by region or interaction. Corrected multiple paired comparisons show significance for DLB/PDD and for Control-LBD groups compared to Control–Low Path. B: The percentage particles +Aβ42 increase in AD dementia and Control–AD Path. C: The percentage particles +Aβ42 also +PHF-tau increase in Control–AD Path, AD dementia, and DLB/PDD. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗∗P < 0.0001 versus Control–Low Path.