Table 4.
Mean level of NSE, MFO and GST activity in An. gambiae s.l. tested population
Kisumu | Ehania-V1 | p value | |||
---|---|---|---|---|---|
N | Mean | N | Mean | ||
α-Naphthyl acetate (μmol α-naphthol/min/mg protein) | 49 | 0.081 ± 0.032 | 50 | 0.187 ± 0.129 | <0.001* |
β-Naphthyl acetate (μmol β-naphthol/min/mg protein) | 45 | 0.084 ± 0.071 | 47 | 0.175 ± 0.120 | <0.001* |
MFO (nmol P450 unit/mg protein) | 47 | 0.074 ± 0.041 | 50 | 0.119 ± 0.113 | 0.277 |
GST (μmol GSH conj/min/mg protein) | 36 | 0.226 ± 0.143 | 44 | 1.778 ± 1.669 | <0.001* |
NSE α activity with substrate alpha-naphthyl acetate (µmol α-naphthol produced/min/mg protein), NSE β level with substrate beta-naphthyl acetate (µmol β-naphthol produced/min/mg protein), MFO multiple function oxidase level (nmol equivalent unit of cytochrome P450/mg protein), GST GST level (nmol GST conjugated/min/mg protein), N number of An. gambiae s.l. tested
* Indicated that enzyme activity or quantity was significantly difference compared with the Kisumu reference susceptible strain (p < 0.001)