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. 2017 Apr 20;17:65. doi: 10.1186/s12890-017-0401-y

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Least square mean improvements in on-treatment reliever use from baseline in patients treated with BUD/FORM MRT or fixed-dose BUD, stratified by baseline reliever use (<1, 1–2 and >2 occasions/day). The error bars represent 95% CI. Statistical comparisons are for BUD/FORM MRT compared with fixed-dose BUD. BUD budesonide, CI confidence intervals, FORM formoterol, MRT maintenance and reliever therapy. * –0.03 occasions/day (95% CI: −0.20, 0.13), p = 0.68; † −0.33 occasions/day (95% CI: −0.48, −0.18), p < 0.0001; ‡ −0.74 occasions/day (95% CI: −1.03, −0.45), p < 0.0001