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. 2017 Apr 20;7:46014. doi: 10.1038/srep46014

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Copyright © 2017, The Author(s)

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(a) Representative ¹³C spectra obtained from the MCD group are compared to those obtained from mice first fed the MCD diet, then normal chow for 1 week. The HP DHA to VitC resonance ratios in the recovery group appear similar to those obtained for controls. (b) Bar graphs obtained for MCDr mice show significant increases in VitC/VitC + DHA and VitC/DHA ratios (p < 0.05) following return to a normal diet, which were not significantly different from baseline mice. (c) Although body weights in MCDr mice returned to normal, there was still significant hepatic steatosis (30%) seen in these animals, 2-fold that seen in the control group. (d) Mercury Orange staining showing decreased thiol content in MCD mice. Significant normalization was seen in the recovery group.