Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Apr 20;7:45523. doi: 10.1038/srep45523

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(a) Morphological changes were examined in MCF10A cells after treatment with TGF-β1 (10 ng/mL) for 4 days. (b) The percentage of apoptotic cells were analyzed in NMuMG and MCF10A cell lines after treatment with TGF-β1 (10 ng/mL) for 48 h. The data shown are the means ± SD of three independent experiments. (c) The time effect of YAP expression was detected by immunoblotting after TGF-β1 (10 ng/mL) treatment for the indicated time in MCF10A cells. (d) The dosage effect of YAP expression was detected by immunoblotting after TGF-β1 treatment (48 h) with the indicated dosage in MCF10A cells. (e) Knockdown of YAP induced apoptosis spontaneously in MCF10A cells, as detected by Annexin V/PI staining. The representative images (left) and statistical data (right) were shown. The data are the means ± SD of three independent experiments. (f) Mesenchymal markers (fibronectin, N-cadherin) were detected by immunoblotting in YAP-knockdown cells after TGF-β1 (5 ng/mL, 48 h) treatment in MCF10A cells.