Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Apr 20;7:45523. doi: 10.1038/srep45523

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(a) EGFR knockdown induced apoptosis spontaneously, as detected by Annexin V/PI double staining. The statistic data shown are the means ± SD of three independent experiments. (b) The protein level of cleaved caspase-3 was examined in EGFR-knockdown cells. (c) Apoptotic cells were examined by Annexin V/PI staining after TGF-β1 (10 ng/mL, 48 h) treatment with or without EGF. Statistical data shown are the means ± SD of three independent experiments. (d) AG1478 inhibited YAP-mediated inhibition of TGF-β1-induced apoptosis. YAP overexpressing cells were treated with AG1478 (1 μM) 1 h before TGF-β1 (10 ng/mL) treatment, and the apoptotic cells were determined by Annexin V/PI double staining. The statistic data shown are the means ± SD of three independent experiments. (e) The protein level of cleaved caspase-3 was examined in YAP overexpressing cells treated with TGF-β1 (10 ng/mL) and AG1478 (1 μM). (f) The protein level of cleaved caspase-3 was examined in YAP overexpressing and EGFR-knockdown cells after TGF-β1 (10 ng/mL) treatment. (g) Apoptotic cells in YAP overexpressing and EGFR-knockdown cells were determined after TGF-β1 (10 ng/mL) treatment by Annexin V/PI double staining. The statistic data shown are the means ± SD of three independent experiments. (h) Apoptotic cells were examined in YAP-knockdown cells with or without EGF (50 ng/mL) by Annexin V/PI double staining. The statistic data shown are the means ± SD of three independent experiments.