Figure 6.

Colloidosome signaling. (A) A glucose oxidase (GOx)-filled colloidosome produces hydrogen peroxide, which induces polymerization of the NIPAM shell of a secondary colloidosome. Consequently, the permeability of the PNIPAM-colloidosome becomes thermoresponsive, influencing the kinetics of an internal reaction. (B) Fluorescence microcopy image of red fluorescent GOx-colloidosomes that induced the polymerization of a green fluorescent shell around a PNIPAM-colloidosome. (C) Kinetics of an enzymatic reaction inside the PNIPAM-colloidosomes before (black) and after (red) polymerization of the NIPAM shell. Adapted with permission from ref (43). Copyright 2016 Wiley.