Table 1. Elevated repeat purity and high polymorphism in dog developmental genes.
| Purity
|
||||
|---|---|---|---|---|
| Repeat locus | Repeat unit | Human | Dog | No. of alleles |
| Alx-4 | PQ | 0.75 | 1.00 | 2 |
| Alx-4 | PQ | 0.93 | 0.96 | 4* |
| Bmp-11 | A | 0.97 | 1.00 | 3 |
| Dlx-2 | G | 0.95 | 0.97 | 5 |
| Hlx-1 | Q | 0.85 | 0.85 | 1 |
| Hox-A2 | A | 0.93 | 1.00 | 2 |
| Hox-A7 | A | 0.83 | 1.00 | 2 |
| Hox-A7 | A | 0.81 | 0.96 | 5* |
| Hox-A7 | D/E | 0.79 | 0.81 | 1 |
| Hox-A7 | 3′utr | 0.67 | 0.82 | 2 |
| Hox-A10 | G | 0.67 | 0.67 | 1 |
| Hox-A11 | A | 0.94 | 1.00 | 5 |
| Hox-A11 | A | — | 1.00 | 2* |
| Hox-A11 | G | 1.00 | 1.00 | 1 |
| Hox-A11 | A | 0.80 | 1.00 | 4* |
| Hox-C13 | G | 0.88 | 1.00 | 4 |
| Hox-D8 | PH | 0.93 | 0.93 | 4 |
| Hox-D8 | P | 0.89 | 0.93 | 1 |
| Hox-D8 | G | 0.83 | 0.92 | 1 |
| Hox-D8 | GP | 0.89 | 0.93 | 3* |
| Hox-D8 | P | 0.88 | 0.92 | 2 |
| Hox-D11 | G | 0.83 | 0.88 | 2 |
| Hox-D11 | A | 0.92 | 0.97 | 2 |
| Hox-D13 | S | 0.89 | 1.00 | 3 |
| Hox-D13 | A | 0.94 | 1.00 | 5 |
| Hox-D13 | A | 0.91 | 0.95 | 5 |
| Runx-2 | Q | 0.93 | 0.96 | 6* |
| Runx-2 | A | 0.88 | 0.95 | 6 |
| Six-3 | G | 0.93 | 1.00 | 5 |
| Six-3 | G | 0.86 | 0.95 | 5 |
| Six-3 | G | 1.00 | 1.00 | 4 |
| Sox-9 | P | 0.87 | 0.96 | 2 |
| Sox-9 | PnQA | 0.86 | 0.94 | 4* |
| Twist | G | 0.90 | 0.95 | 7* |
| Twist | G | 1.00 | 1.00 | 5 |
| Zic-2 | A | 0.85 | 0.89 | 1 |
| Zic-2 | H | 1.00 | 1.00 | 2 |
Purity was computed by dividing the number of bases that deviated from the canonical repeat unit (borders defined by amino acid translation) by the total length of the repeat and subtracting from one.
*
Includes distinct alleles of equal length, identified by variable imperfections within the repeat consistent with independent expansion/contraction events.