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. 2017 Apr 20;11:100. doi: 10.3389/fncel.2017.00100

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Copyright © 2017 Ju, Yang, Lei, Xia, Luo, Ji, Martynyuk and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effects of ketamine treatment on body weight after electric foot shocks procedures. (A) Percentage of time freezing, in mice, to the conditioned tone (CS) following tone-shock pairings during the conditioned fear trials. (B,C) IFS mice had lower body weight compared with the Veh group, and both Flx and ketamine alleviated the loss of body weight induced by IFS. There was no different in body weight among the varying doses of ketamine groups. Data are presented as mean ± SEM (n = 50 in A; n = 15 in per group). *P < 0.05, **P < 0.01, ***P < 0.001 compared with the Veh group.