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. 2004 Dec 17;101(52):18147–18152. doi: 10.1073/pnas.0408260101

Table 2. Selection of the 50 genes most up-regulated in the INV and/or MET libraries with respect to the Br_N library from normal mammary epithelium.

Gene symbol Br_N INV MET Unigene ID Genetic map
Transcription factors/chromatin/nuclear proteins
    HNRPC 1 35 20 476302 14q11.2
    HIF1A 0 0* 31 412416 14q21-q24
    HMGA1 1 1* 26 57301 6p21
    RMP 0 23 0* 7943 19q12
    H2AFZ 0 1* 23 119192 4q24
    SRCAP 1 19 0* 136227 16p11.2
    DHX9 0 0* 17 374524 1q25
    PTMA 1 1* 15 459927 2q35-q36
    ZNF9 0 0* 12 2110 3q21
    HMGB1 2 7* 22 434102 13q12
    SFRS6 1 0* 9 6891 20q12-q13.1
    NME1 0 1* 8 118638 17q21.3
    ADNP 0 7 0* 448540 20q13.13
Cell cycle/apoptosis/cell growth
    CEB1 0 1* 20 26663 4q22.1-q23
    TGFA 0 15 0* 170009 2p13
    CTGF 0 13 0* 410037 6q23.1
    CCNA2 0 5 1* 85137 4q25-q31
    SPY1 3 11 0* 511956 2p23.3
Membrane proteins/antigens/receptors/adhesion
    GAGED2 0 0* 36 112208 Xp11.22-p11.21
    IFITM3 0 1* 27 374650 11p15.5
    STEAP 0 0* 9 61635 7q21
Signal transduction
    DUSP23 1 1* 22 425801 1q23.1
    GNG11 0 0* 19 83381 7q31-q32
    PTPN1 0 19 0* 418004 20q13.1-q13.2
    YWHAZ 0 1* 15 386834 8q23.1
    GNB2L1 3 1* 30 5662 5q35.3
    DGKQ 0 8 0* 99932 4p16.3
Secreted and ECM proteins
    IGFBP4 1 1* 12 1516 17q12-q21.1
    FDC-SP 0 9 0* 320147 4q13
    EDN2 1 7 0* 1407 1p34
    FN1 0 1* 6 418138 2q34
Cytoskeleton
    CYFIP1 0 14 4 26704 15q11
    FSCN1 0 1* 23 118400 7p22
    CAP1 1 0* 11 104125 1p34.2
Protein synthesis, transport, and degradation
    SAE1 1 0* 18 32748 19q13.33
    CCT5 1 2* 17 1600 5p15.31
    UBA52 2 3* 31 5308 19p13.1-p12
    TRAP1 0 0* 14 183803 16p13.3
    RPN2 0 0* 11 406532 20q12-q13.1
    PPIA 17 27* 159 356331 7p13-p11.2
    YKT6 1 8 0* 296244 7p15.1
    HSPA8 7 0 31 180414 11q24.1
    TPT1 48 6 90 374596 13q12-q14
Metabolism
    LDHA 3 1* 68 2795 11p15.4
    NNMT 1 0* 16 364345 11q23.1
    ENO1 0 0* 11 433455 1p36.3-p36.2
    AHCY 1 1* 9 388004 20cen-q13.1
Others
    SNCAIP 0 23 0* 24948 5q23.1-q23.3
    ANKRD10 0 19 0* 164969 13q34
    OBTP 1 1* 12 525899 6p21.31

The frequency for each tag is given for a 10,000-tag library. Asterisks refer to tags whose P value is not statistically significant in one of the libraries. Values in italics indicate a P value that is statistically significant, but with expression in the opposing direction in one of the libraries. The complete data are published in Tables 3-8.