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Effects of DPP-4 inhibition on regulation of plasma glucose. Reproduced with permission from Herman GA, Stein PP, Thornberry NA, Wagner JA. Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: focus on sitagliptin. Clin Pharmacol Ther 2007; 81: 761-7. DPP-4, dipeptidyl peptidase-4; GIP, glucose-dependent insulinotropic peptide.
