Figure 6. LPA ameliorates the hypoxia-induced mitochondrial dysfunction in C28/I2 cells.

C28/I2 cells were treated with 0 or 10 nM LPA and then were incubated for 24 or 48 h under hypoxia, and then the percentage of mitochondrial superoxide levels (A), of ROS level (B), of MMP (C) and of Complex IV activity (D) were assayed respectively. All results were averaged for three independent experiments. *P<0.05, **P<0.01 or ***P< 0.001.