Figure 5.

mPFC activity during learning influenced CA1 activity most strongly when the subsequent reversal is learned most quickly. Granger values were calculated during early learning (A) and stable performance (B) for trials that preceded reversals that were learned at different rates. Significant influence of mPFC on CA1 was only observed when animals learned the subsequent reversal quickly, in ≤ 3 trials (see main text). * above columns indicate significantly different than chance calculated by permutation tests.