Figure 3.

The gemcitabine cascades described in Garcĺa-Manteiga et al.¹⁸, here modeled with bStyle. The user has selected the phosphorylation by deoxycytidine kinase (dCK) of gemcitabine (dFdC) to its monophosphate dFdC-MP. The entire transformation is presented in the toolbar with a familiar symbolism. Additional nonuser-selected entities are presented as well to provide the most complete representation of the modeled process. In this case, the competition of gemcitabine with the natural nucleoside deoxycytidine diphosphate (dCTP) modeled as the inhibition on dCK via binding with dCTP is clear. Link numbers in the toolbar stand for the corresponding stoichiometric coefficients that can be edited with a click as happens for the rates.