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. Author manuscript; available in PMC: 2017 Apr 20.
Published in final edited form as: Curr Top Membr. 2016 Jun 14;78:287–311. doi: 10.1016/bs.ctm.2016.05.001

Figure 4. Solution NMR structure of the DIII–DIV inactivation loop.

Figure 4

Three views of the putative sodium channel inactivation loop segment (PDB ID code 1BYY). The hydrophobic sequence of residues (IFM), demonstrated to be critical for NaV1.5 inactivation, are highlighted in space-filling representation. The remainder of the segment is shown in ribbon representation. Kevin R. DeMarco.