. 2016 Aug 24;49(2):494–501. doi: 10.4143/crt.2016.129

Table 2.

Germ cell tumor incidence rates, 2005-2012

Group	Total				Male				Female
Group	Case, n (%)	CR	ASR^a)	95% CI	Case, n (%)	CR	ASR^a)	95% CI	Case, n (%)	CR	ASR^a)	95% CI
Total	654 (100.0)	0.165	0.179	0.166-0.193	504 (100.0)	0.254	0.263	0.240-0.286	150 (100.0)	0.076	0.089	0.075-0.104
Age (yr)
0-14	296 (45.3)	0.434	0.093	0.385-0.484	205 (40.7)	0.576	0.124	0.497-0.654	91 (40.7)	0.280	0.060	0.222-0.337
15-29	308 (47.1)	0.365	0.074	0.324-0.406	261 (51.8)	0.594	0.121	0.522-0.667	47 (51.8)	0.116	0.024	0.083-0.149
≥ 30	50 (7.6)	0.021	0.012	0.015-0.026	38 (7.5)	0.032	0.019	0.022-0.042	12 (7.5)	0.010	0.006	0.004-0.015
Primary site
Pineal (C753)	226 (34.6)	0.057	0.062	0.053-0.070	211 (41.9)	0.106	0.111	0.096-0.126	15 (41.9)	0.008	0.008	0.004-0.012
Nonpineal (C700-729, 751-752)	428 (65.4)	0.108	0.118	0.107-0.129	293 (58.1)	0.148	0.152	0.134-0.170	135 (58.1)	0.068	0.081	0.067-0.095
Suprasellar region (C715, 719, 729, 751)	317 (48.5)	0.080	0.087	0.078-0.097	204 (40.5)	0.103	0.105	0.091-0.120	113 (40.5)	0.057	0.068	0.055-0.081
Ventricle (C715)	43 (6.6)	0.011	0.012	0.008-0.015	35 (6.9)	0.018	0.018	0.012-0.024	8 (6.9)	0.004	0.005	0.002-0.009
Brain, NOS (C719)	229 (35.0)	0.058	0.064	0.056-0.072	145 (28.8)	0.073	0.075	0.063-0.088	84 (28.8)	0.042	0.052	0.040-0.063
Nervous system, NOS (C729)	1 (0.2)	0.000	0.000	0.000-0.001	1 (0.2)	0.001	0.001	–0.001-0.002	0 (0.2)	-	-	-
Pituitary gland (C751)	44 (6.7)	0.011	0.011	0.008-0.015	23 (4.6)	0.012	0.011	0.007-0.016	21 (4.6)	0.011	0.011	0.006-0.016
Cerebrum (C710)	62 (9.5)	0.016	0.017	0.013-0.022	53 (10.5)	0.027	0.029	0.021-0.037	9 (10.5)	0.005	0.005	0.002-0.009
All other sites	49 (7.5)	0.012	0.013	0.009-0.017	36 (7.1)	0.018	0.018	0.012-0.024	13 (7.1)	0.007	0.008	0.004-0.012
Histology
Germinoma	497 (76.0)	0.125	0.134	0.122-0.146	385 (76.4)	0.194	0.197	0.177-0.217	112 (76.4)	0.057	0.066	0.053-0.078
Nongerminomatous GCT	116 (17.7)	0.029	0.034	0.027-0.040	85 (16.9)	0.043	0.047	0.037-0.057	31 (16.9)	0.016	0.019	0.012-0.026
Nongerminomatous excluding mixed germ cell	26 (4.0)	0.007	0.008	0.005-0.010	20 (4.0)	0.010	0.011	0.006-0.016	6 (4.0)	0.003	0.004	0.001-0.006
Mixed germ cell	90 (13.8)	0.023	0.026	0.021-0.031	65 (12.9)	0.033	0.036	0.027-0.044	25 (12.9)	0.013	0.016	0.010-0.022
Teratoma	41 (6.3)	0.010	0.012	0.008-0.016	34 (6.7)	0.017	0.019	0.013-0.026	7 (6.7)	0.004	0.004	0.001-0.007

CR, crude rate; ASR, age-standardized rate; CI, confidence interval; NOS, not otherwise specified; GCT, germ cell tumor.

^a)

Adjusted with the year 2000 United States standard population.