Effect of maternal hypothyroxinemia over Schaffer collateral → CA1 synaptic function
of their progeny. A, Input-output (I/O) curves display the mean fEPSP amplitude +
sem for control (Co) (•) and MMIo (○) rat hippocampal slices. At least
three different animals were used for each experimental condition. B, Effect of
maternal hypothyroxinemia over LTP induction of their progeny. Mean fEPSP amplitude +
sem obtained from slices of control (•) and MMIo rats (○). *,
P < 0.05; control (n = 9) and MMIo (n = 6). C, The traces
correspond to fEPSP measured in the stratum radiatum of representative experiments for
each condition (control and MMIo) before TBS (gray line) and 30 min
after TBS (black line). ms, msec; Pre, before; Post, after.