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. 2017 Apr 11;23:1751–1758. doi: 10.12659/MSM.900205

Figure 5.

Figure 5

Knockdown of P53 in NCI-H929 and A549 cells relieved the inhibitory effects of PRAL on cell proliferation. (A) Both NCI-H929 and A549 cells were transfected with PRAL-expressing plasmid with or without siNC/siP53 and the relative transcript level of PRAL was explored in these experimental cells.* P<0.05, vs. Control in NCI-H929 cells. # P<0.05, vs. Control in A549 cells. (B) Both NCI-H929 and A549 cells were transfected with PRAL-expressing plasmid with or without siNC/siP53 and the mRNA levels of P53 were explored in these experimental cells. * P<0.05, vs. Control in NCI-H929 cells. # P<0.05, vs. Control in A549 cells. (C) NCI-H929 cells were transfected with PRAL-expressing plasmid with or without siNC/siP53 and the proliferative rate was explored in these experimental cells. * P<0.05, vs. Control. (D) A549 cells were transfected with PRAL-expressing plasmid with or without siNC/siP53 and the proliferative rate was explored in these experimental cells. # P<0.05, vs. Control.