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Male fertility and negative feedback in GnRH γ2 KO mice. A, Histograms showing the mean + sem numbers of litters and pups per litter born to breeding pairs in which wild-type females were mated with either GnRH γ2 KO (GnRH-Cre, fg2/fg2; n = 5) or control (GnRH-Cre, n = 5) mice. B, Histograms showing mean + sem. LH levels of intact and goandectomized (GDX) GnRH γ2 KO (n = 5) and control (fg2/fg2; n = 5) mice. *, P < 0.05; ***, P < 0.001.
