Table 1. Results of the genotyping of pups/embryos by crossing of Ngly1−/+, or Ngly1−/+;Engase−/− mice in the C57BL/6 background.
| Stage | Genotype | Number of viable embryos/pups | Number of inviable embryos/pups |
|---|---|---|---|
| E14.5 | Ngly1+/+ | 18 (21.95) [25.00] | 0 |
| Ngly1−/+ | 50 (60.98) [50.00] | 0 | |
| Ngly1−/− | 14 (17.07) [25.00] | 0 | |
| E16.5 | Ngly1+/+ | 56 (28.00) [25.00] | 0 |
| Ngly1−/+ | 113 (56.50) [50.00] | 0 | |
| Ngly1−/− | 31 (15.50) [25.00] | 0 | |
| Ngly1+/+;Engase−/− | 20 (22.73) [25.00] | 0 | |
| Ngly1−/+;Engase−/− | 52 (59.09) [50.00] | 0 | |
| Ngly1−/−;Engase−/− | 16 (18.18) [25.00] | 0 | |
| E17.5 | Ngly1+/+ | 21 (28.77) [25.00] | 0 |
| Ngly1−/+ | 38 (52.05) [50.00] | 1 | |
| Ngly1−/− | 14 (19.18) [25.00] | 7 | |
| E18.5 | Ngly1+/+ | 23 (31.08) [25.00] | 0 |
| Ngly1−/+ | 38 (51.35) [50.00] | 1 | |
| Ngly1−/− | 13 (17.57) [25.00] | 5 | |
| P0 | Ngly1+/+ | 22 | − |
| Ngly1−/+ | 35 | − | |
| Ngly1−/− | 0 | − | |
| 2 wks | Ngly1+/+ | 49 | − |
| Ngly1−/+ | 84 | − | |
| Ngly1−/− | 0 | − |
E: Embryonic day, P: Postnatal day, wks: weeks, V: Viable, IV: Inviable.
(number): birth rates (%), [number]: expected (%).