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. 2017 Apr 20;12(4):e0175800. doi: 10.1371/journal.pone.0175800

Table 3. Twin intra-pair analyses.

Mean Intra-pair Difference Intra-pair Correlation
Region Volume Monozygotic Dizygotic Sig. Diff. Monozygotic 95% CI Dizygotic 95% CI
Brain Total 25.7 93.4 ** 0.939** 0.85, 0.98 0.478 -0.023, 0.79
Right 13.1 53.7 ** 0.923** 0.81, 0.97 0.424 -0.091, 0.76
Left 12.5 43.4 ** 0.919** 0.80, 0.97 0.487 -0.012, 0.79
TGM 19.8 54.5 ** 0.955** 0.89, 0.98 0.647** 0.22, 0.87
RGM 10.1 26.0 ** 0.936** 0.84, 0.97 0.653** 0.23, 0.87
LGM 10.4 25.0 ** 0.935** 0.84, 0.97 0.667** 0.26, 0.87
TWM 19.7 45.1 ** 0.871** 0.70, 0.95 0.358 -0.17, 0.73
RWM 9.39 31.6 ** 0.884** 0.73, 0.95 0.127 -0.39, 0.59
LWM 10.4 22.0 ** 0.851** 0.65, 0.94 0.366 -0.16, 0.73
CSF 30.4 49.7 ** 0.866** 0.69, 0.95 0.876** 0.67, 0.96
Cerebrum Total 21.9 79.5 ** 0.927** 0.82, 0.97 0.482 -0.018, 0.79
Right 11.6 39.9 ** 0.923** 0.81, 0.97 0.496 0.00030, 0.80
Left 11.1 39.0 ** 0.924** 0.81, 0.97 0.462 -0.043, .78
TGM 17.8 45.5 ** 0.942** 0.86, 0.98 0.666** 0.25, 0.87
RGM 9.46 23.0 ** 0.933** 0.83, 0.97 0.665** 0.25, 0.87
LGM 8.81 22.0 ** 0.946** 0.87, 0.98 0.659** 0.24, 0.87
TWM 17.7 41.7 ** 0.878** 0.71, 0.95 0.339 -0.19, 0.71
RWM 8.33 20.8 ** 0.896** 0.75, 0.96 0.332 -0.20, 0.71
LWM 9.54 20.8 ** 0.855** 0.66, 0.94 0.348 -0.18, 0.72
Cerebellum Total 3.17 9.26 ** 0.881** 0.72, 0.95 0.394 -0.13, 0.74
Right 2.28 5.13 ** 0.823** 0.60, 0.93 0.342 -0.18, 0.72
Left 2.38 4.45 ** 0.788** 0.53, 0.91 0.445 -0.066, 0.77
TGM 3.23 7.57 ** 0.884** 0.72, 0.95 0.448 -0.062, 0.77
RGM 1.93 4.07 ** 0.844** 0.64, 0.94 0.425 -0.089, 0.76
LGM 2.20 3.74 * 0.754** 0.47, 0.90 0.466 -0.039, 0.78
TWM 1.72 2.78 ** 0.870** 0.70, 0.95 0.733** 0.37, 0.90
RWM 0.933 1.46 ** 0.843** 0.64, 0.94 0.697** 0.31, 0.89
LWM 0.863 1.37 * 0.855** 0.66, 0.94 0.753** 0.41, 0.91
Frontal Total 12.6 33.5 ** 0.922** 0.81, 0.97 0.483 -0.017, 0.79
Right 9.07 13.6 * 0.826** 0.61, 0.93 0.573* 0.11, 0.83
Left 7.38 20.3 ** 0.926** 0.82,0.97 0.302 -0.23, 0.69
TGM 7.57 18.1 ** 0.937** 0.85, 0.98 0.667** 0.26, 0.87
RGM 5.07 8.14 ** 0.864** 0.68, 0.95 0.709** 0.33, 0.89
LGM 4.01 10.8 ** 0.956** 0.89, 0.98 0.566* 0.10, 0.83
TWM 6.28 18.8 ** 0.912** 0.79, 0.97 0.346 -0.18, 0.72
RWM 4.25 7.90 ** 0.834** 0.62, 0.93 0.485 -0.014, 0.79
LWM 4.25 11.1 ** 0.880** 0.72, 0.95 0.119 -0.40, 0.58
Temporal Total 4.63 19.0 ** 0.954** 0.89, 0.98 0.433 -0.08, 0.76
Right 2.92 9.28 ** 0.923** 0.81, 0.97 0.409 -0.11, 0.75
Left 2.70 9.69 ** 0.954** 0.88, 0.98 0.454 -0.054, 0.78
TGM 4.27 10.6 ** 0.943** 0.86, 0.98 0.494 -0.0017, 0.80
RGM 2.48 5.00 ** 0.910** 0.78, 0.96 0.449 -0.060, 0.77
LGM 2.14 5.70 ** 0.949** 0.87, 0.98 0.517* 0.028, 0.81
TWM 3.49 9.02 ** 0.922** 0.81, 0.97 0.431 -0.082, 0.76
RWM 1.61 4.76 ** 0.922** 0.81, 0.70 0.404 -0.11, 0.75
LWM 2.24 4.27 ** 0.882** 0.72, 0.95 0.459 -0.047, 0.78
Parietal Total 5.55 16.6 ** 0.896** 0.75, 0.96 0.355 -0.17, 0.72
Right 3.02 8.80 ** 0.857** 0.67, 0.94 0.359 -0.17, 0.73
Left 3.31 8.08 ** 0.869** 0.69, 0.95 0.331 -0.20, 0.71
TGM 4.44 8.91 ** 0.888** 0.73, 0.96 0.594* 0.14, 0.84
RGM 2.15 4.76 ** 0.861** 0.68, 0.94 0.589* 0.13, 0.84
LGM 2.38 4.40 ** 0.866** 0.69, 0.95 0.574* 0.11, 0.83
TWM 3.67 9.60 ** 0.923** 0.81, 0.97 0.383 -0.14, 0.74
RWM 2.12 4.85 ** 0.888** 0.73, 0.96 0.362 -0.16, 0.73
LWM 2.31 4.95 ** 0.904** 0.77, 0.96 0.394 -0.13, 0.74
Occipital Total 5.94 12.7 ** 0.757** 0.47, 0.90 0.495 -0.00066, 0.80
Right 4.16 8.91 ** 0.561* 0.16, 0.80 0.017 -0.51, 0.48
Left 5.04 5.17 - 0.626** 0.25, 0.84 0.708** 0.33, 0.89
TGM 3.34 6.72 ** 0.743** 0.45, 0.85 0.557* 0.085, 0.83
RGM 2.07 5.33 ** 0.650** 0.29, 0.85 0.103 -0.41, 0.57
LGM 3.05 3.14 - 0.563** 0.16, 0.81 0.635** 0.20, 0.86
TWM 3.42 6.20 ** 0.834** 0.62, 0.93 0.659** 0.24, 0.87
RWM 2.43 3.87 ** 0.666** 0.32, 0.86 0.248 -0.28, 0.66
LWM 2.45 2.56 - 0.760** 0.48, 0.90 0.804** 0.51, 0.93
Brainstem Total 1.34 2.40 ** 0.838** 0.63, 0.93 0.693** 0.30, 0.88
Right 0.700 1.22 ** 0.843** 0.64, 0.94 0.663** 0.25, 0.87
Left 0.693 1.20 ** 0.806** 0.57, 0.92 0.706** 0.32, 0.89

T = total, R = right, L = left, GM = grey matter, WM = white matter, CSF = cerebrospinal fluid. Volumes are adjusted for ICV and expressed in cm3;

- indicates p≥0.05;

* indicates p<0.05;

** indicates p<0.01.