Table 3. Twin intra-pair analyses.
Mean Intra-pair Difference | Intra-pair Correlation | |||||||
---|---|---|---|---|---|---|---|---|
Region | Volume | Monozygotic | Dizygotic | Sig. Diff. | Monozygotic | 95% CI | Dizygotic | 95% CI |
Brain | Total | 25.7 | 93.4 | ** | 0.939** | 0.85, 0.98 | 0.478 | -0.023, 0.79 |
Right | 13.1 | 53.7 | ** | 0.923** | 0.81, 0.97 | 0.424 | -0.091, 0.76 | |
Left | 12.5 | 43.4 | ** | 0.919** | 0.80, 0.97 | 0.487 | -0.012, 0.79 | |
TGM | 19.8 | 54.5 | ** | 0.955** | 0.89, 0.98 | 0.647** | 0.22, 0.87 | |
RGM | 10.1 | 26.0 | ** | 0.936** | 0.84, 0.97 | 0.653** | 0.23, 0.87 | |
LGM | 10.4 | 25.0 | ** | 0.935** | 0.84, 0.97 | 0.667** | 0.26, 0.87 | |
TWM | 19.7 | 45.1 | ** | 0.871** | 0.70, 0.95 | 0.358 | -0.17, 0.73 | |
RWM | 9.39 | 31.6 | ** | 0.884** | 0.73, 0.95 | 0.127 | -0.39, 0.59 | |
LWM | 10.4 | 22.0 | ** | 0.851** | 0.65, 0.94 | 0.366 | -0.16, 0.73 | |
CSF | 30.4 | 49.7 | ** | 0.866** | 0.69, 0.95 | 0.876** | 0.67, 0.96 | |
Cerebrum | Total | 21.9 | 79.5 | ** | 0.927** | 0.82, 0.97 | 0.482 | -0.018, 0.79 |
Right | 11.6 | 39.9 | ** | 0.923** | 0.81, 0.97 | 0.496 | 0.00030, 0.80 | |
Left | 11.1 | 39.0 | ** | 0.924** | 0.81, 0.97 | 0.462 | -0.043, .78 | |
TGM | 17.8 | 45.5 | ** | 0.942** | 0.86, 0.98 | 0.666** | 0.25, 0.87 | |
RGM | 9.46 | 23.0 | ** | 0.933** | 0.83, 0.97 | 0.665** | 0.25, 0.87 | |
LGM | 8.81 | 22.0 | ** | 0.946** | 0.87, 0.98 | 0.659** | 0.24, 0.87 | |
TWM | 17.7 | 41.7 | ** | 0.878** | 0.71, 0.95 | 0.339 | -0.19, 0.71 | |
RWM | 8.33 | 20.8 | ** | 0.896** | 0.75, 0.96 | 0.332 | -0.20, 0.71 | |
LWM | 9.54 | 20.8 | ** | 0.855** | 0.66, 0.94 | 0.348 | -0.18, 0.72 | |
Cerebellum | Total | 3.17 | 9.26 | ** | 0.881** | 0.72, 0.95 | 0.394 | -0.13, 0.74 |
Right | 2.28 | 5.13 | ** | 0.823** | 0.60, 0.93 | 0.342 | -0.18, 0.72 | |
Left | 2.38 | 4.45 | ** | 0.788** | 0.53, 0.91 | 0.445 | -0.066, 0.77 | |
TGM | 3.23 | 7.57 | ** | 0.884** | 0.72, 0.95 | 0.448 | -0.062, 0.77 | |
RGM | 1.93 | 4.07 | ** | 0.844** | 0.64, 0.94 | 0.425 | -0.089, 0.76 | |
LGM | 2.20 | 3.74 | * | 0.754** | 0.47, 0.90 | 0.466 | -0.039, 0.78 | |
TWM | 1.72 | 2.78 | ** | 0.870** | 0.70, 0.95 | 0.733** | 0.37, 0.90 | |
RWM | 0.933 | 1.46 | ** | 0.843** | 0.64, 0.94 | 0.697** | 0.31, 0.89 | |
LWM | 0.863 | 1.37 | * | 0.855** | 0.66, 0.94 | 0.753** | 0.41, 0.91 | |
Frontal | Total | 12.6 | 33.5 | ** | 0.922** | 0.81, 0.97 | 0.483 | -0.017, 0.79 |
Right | 9.07 | 13.6 | * | 0.826** | 0.61, 0.93 | 0.573* | 0.11, 0.83 | |
Left | 7.38 | 20.3 | ** | 0.926** | 0.82,0.97 | 0.302 | -0.23, 0.69 | |
TGM | 7.57 | 18.1 | ** | 0.937** | 0.85, 0.98 | 0.667** | 0.26, 0.87 | |
RGM | 5.07 | 8.14 | ** | 0.864** | 0.68, 0.95 | 0.709** | 0.33, 0.89 | |
LGM | 4.01 | 10.8 | ** | 0.956** | 0.89, 0.98 | 0.566* | 0.10, 0.83 | |
TWM | 6.28 | 18.8 | ** | 0.912** | 0.79, 0.97 | 0.346 | -0.18, 0.72 | |
RWM | 4.25 | 7.90 | ** | 0.834** | 0.62, 0.93 | 0.485 | -0.014, 0.79 | |
LWM | 4.25 | 11.1 | ** | 0.880** | 0.72, 0.95 | 0.119 | -0.40, 0.58 | |
Temporal | Total | 4.63 | 19.0 | ** | 0.954** | 0.89, 0.98 | 0.433 | -0.08, 0.76 |
Right | 2.92 | 9.28 | ** | 0.923** | 0.81, 0.97 | 0.409 | -0.11, 0.75 | |
Left | 2.70 | 9.69 | ** | 0.954** | 0.88, 0.98 | 0.454 | -0.054, 0.78 | |
TGM | 4.27 | 10.6 | ** | 0.943** | 0.86, 0.98 | 0.494 | -0.0017, 0.80 | |
RGM | 2.48 | 5.00 | ** | 0.910** | 0.78, 0.96 | 0.449 | -0.060, 0.77 | |
LGM | 2.14 | 5.70 | ** | 0.949** | 0.87, 0.98 | 0.517* | 0.028, 0.81 | |
TWM | 3.49 | 9.02 | ** | 0.922** | 0.81, 0.97 | 0.431 | -0.082, 0.76 | |
RWM | 1.61 | 4.76 | ** | 0.922** | 0.81, 0.70 | 0.404 | -0.11, 0.75 | |
LWM | 2.24 | 4.27 | ** | 0.882** | 0.72, 0.95 | 0.459 | -0.047, 0.78 | |
Parietal | Total | 5.55 | 16.6 | ** | 0.896** | 0.75, 0.96 | 0.355 | -0.17, 0.72 |
Right | 3.02 | 8.80 | ** | 0.857** | 0.67, 0.94 | 0.359 | -0.17, 0.73 | |
Left | 3.31 | 8.08 | ** | 0.869** | 0.69, 0.95 | 0.331 | -0.20, 0.71 | |
TGM | 4.44 | 8.91 | ** | 0.888** | 0.73, 0.96 | 0.594* | 0.14, 0.84 | |
RGM | 2.15 | 4.76 | ** | 0.861** | 0.68, 0.94 | 0.589* | 0.13, 0.84 | |
LGM | 2.38 | 4.40 | ** | 0.866** | 0.69, 0.95 | 0.574* | 0.11, 0.83 | |
TWM | 3.67 | 9.60 | ** | 0.923** | 0.81, 0.97 | 0.383 | -0.14, 0.74 | |
RWM | 2.12 | 4.85 | ** | 0.888** | 0.73, 0.96 | 0.362 | -0.16, 0.73 | |
LWM | 2.31 | 4.95 | ** | 0.904** | 0.77, 0.96 | 0.394 | -0.13, 0.74 | |
Occipital | Total | 5.94 | 12.7 | ** | 0.757** | 0.47, 0.90 | 0.495 | -0.00066, 0.80 |
Right | 4.16 | 8.91 | ** | 0.561* | 0.16, 0.80 | 0.017 | -0.51, 0.48 | |
Left | 5.04 | 5.17 | - | 0.626** | 0.25, 0.84 | 0.708** | 0.33, 0.89 | |
TGM | 3.34 | 6.72 | ** | 0.743** | 0.45, 0.85 | 0.557* | 0.085, 0.83 | |
RGM | 2.07 | 5.33 | ** | 0.650** | 0.29, 0.85 | 0.103 | -0.41, 0.57 | |
LGM | 3.05 | 3.14 | - | 0.563** | 0.16, 0.81 | 0.635** | 0.20, 0.86 | |
TWM | 3.42 | 6.20 | ** | 0.834** | 0.62, 0.93 | 0.659** | 0.24, 0.87 | |
RWM | 2.43 | 3.87 | ** | 0.666** | 0.32, 0.86 | 0.248 | -0.28, 0.66 | |
LWM | 2.45 | 2.56 | - | 0.760** | 0.48, 0.90 | 0.804** | 0.51, 0.93 | |
Brainstem | Total | 1.34 | 2.40 | ** | 0.838** | 0.63, 0.93 | 0.693** | 0.30, 0.88 |
Right | 0.700 | 1.22 | ** | 0.843** | 0.64, 0.94 | 0.663** | 0.25, 0.87 | |
Left | 0.693 | 1.20 | ** | 0.806** | 0.57, 0.92 | 0.706** | 0.32, 0.89 |
T = total, R = right, L = left, GM = grey matter, WM = white matter, CSF = cerebrospinal fluid. Volumes are adjusted for ICV and expressed in cm3;
- indicates p≥0.05;
* indicates p<0.05;
** indicates p<0.01.