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. 2017 Apr 20;12(4):e0176001. doi: 10.1371/journal.pone.0176001

Table 5. Minimum detectable effect sizes for testing whether two means are different under the given circumstances of the present study (load of flat ACF, load of colonic tumors and load of small intestinal tumors (log-transformed)).

Parameter N Standard deviation Power Minimum detectable effect Reference values
Salmon Beef RM1
Load of colonic flat ACF 18 1.38 0.8 1.33 -2.92 -2.39 -0.25
0.5 0.93
0.2 0.53
Colonic tumor load 0.86 0.8 0.82 0.16 0.28 1.66
0.5 0.58
0.2 0.33
Small intestinal tumor load 1.06 0.8 1.02 1.21 2.55 3.20
0.5 0.71
0.2 0.41

Calculations were based on the observed standard deviations of the log-transformed means, and a group size of 20 animals. Three different levels of power were chosen, and calculated values for the minimum detectable effects are given. Exemplary log-transformed reference values for the parameters of the Salmon, Beef and RM1 group illustrate the relevance of the effect sizes.