Figure 2.

Three representative examples of pulsatile LH secretion in prepubertal (○, 4 week old) male C57BL/6 mice and in the same mice in adulthood (●, 16 weeks old). Panels on the left illustrate circulating levels of whole blood LH over a 6-hour sampling period. Starting at 7:00 am, whole blood samples were collected at 10-minute intervals. Panels on the right illustrate the secretion rate of LH after deconvolution analysis, with open circles on the x-axis indicating the onset of a pulse in LH secretion, as determined by deconvolution analysis. Output parameters and comparisons between LH secretion at 4 and 16 weeks of age are summarized in Table 2.