Table 1. Clinical characteristics of patients.
| Variables | Hemodialysis (N = 343) | Control (N = 252) |
P value |
|---|---|---|---|
| Age(yr) | 63.2±12.3 | 57.8±11.8 | <0.001 |
| Male | 155 (45.2%) | 128 (50.8%) | 0.18 |
| BMI (kg/m2) | <0.001 | ||
| <24 | 246 (72.1%) | 73 (30.3%) | |
| 24–30 | 87 (25.5%) | 129 (53.5%) | |
| >30 | 8 (2.4%) | 39 (16.2%) | |
| DM (%) | 105 (30.6%) | 98 (38.9%) | 0.04 |
| AST (IU/L) | 19.8±8.9 | 35.9±23.0 | <0.001 |
| ALT (IU/L) | 16.5±12.2 | 41.8±30.6 | <0.001 |
| Bilirubin (mg/dL) | 0.4±0.6 | 1.0±1.0 | <0.001 |
| Albumin (g/dL) | 3.9±0.3 | 4.6±0.4 | <0.001 |
| Fasting sugar (mg/dL) | 147.9±70.5 | 113.0±31.5 | <0.001 |
| HDL, male< 40, female < 50(mg/dL) | 171 (51.2%) | 38 (17.8%) | <0.001 |
| LDL (mg/dL) | 87.5±30.9 | 99.7±32.2 | <0.001 |
| Total cholesterol (mg/dL) | 163.1±39.5 | 182.4±37.2 | <0.001 |
| VLDL(mg/dL) | 29.0±17.3 | 24.9±12.4 | 0.004 |
| Triglyceride >150 (mg/dL) | 126 (37.2%) | 56 (26.4%) | 0.009 |
| Platelet<150 (1000/μL) | 93 (27.4%) | 21 (20.4%) | 0.16 |
| LSM (kPa) | 6.2 (4.7–8.4) | 5.4 (4.4–8.5) | 0.004 |
| CAP (dB/m) | 234 (201–268) | 276 (239–311) | <0.001 |
| Serum iron (mg/dL) | 69.4±30.1 | Not available | - |
| TIBC(mg/dL) | 207.0±37.7 | Not available | - |
| Ferritin (ng/mL) | 432.2 (287–617.1) | Not available | - |
| Hemoglobin (g/dL) | 10.5±1.2 | Not available | - |
| Ultrasound steatosis grade | <0.001 | ||
| S1 | 55 (16.0%) | 61 (24.2%) | |
| S2 | 32 (9.3%) | 105 (41.7%) | |
| S3 | 4 (1.2%) | 14 (5.6%) | |
| CAP | <0.001 | ||
| S1 | 63 (18.4%) | 38 (15.1%) | |
| S2 | 53 (15.5%) | 59 (23.4%) | |
| S3 | 47 (13.7%) | 95 (37.7%) |
Data are shown as mean±SD, but LSM, and CAP are shown as median (interquantile). BMI, body mass index; DM, diabetes mellitus; ALT, alanine aminotransferase; AST, aspartate aminotransferase; HDL, High-density lipoprotein; CAP, Controlled Attenuation Parameter; LSM, liver stiffness measurement; LDL, low-density lipoprotein; VLDL, Very-low-density lipoprotein; TIBC, total iron-binding capacity