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. 2017 Apr 20;12(4):e0176027. doi: 10.1371/journal.pone.0176027

Table 3. Factors associated with US-identified HS (logistic regression).

Variables Hemodialysis Control
Univariate Multivariate Univariate Multivariate
OR (95% CI) P OR P OR (95% CI) P OR P
Age 1.01 (0.99–1.03) 0.370 - 1.00 (0.98–1.03) 0.718 -
Male 0.99 (0.61–1.61) 0.980 - 0.71 (0.41–1.23) 0.218 -
BMI (kg/m2) 1.25 (1.16–1.36) <0.001 1.21 (1.11–1.32) <0.001 1.20 (1.10–1.31) <0.001 1.15 (1.02–1.29) 0.027
DM 1.52 (0.92–2.52) 0.100 - 3.25 (1.71–6.17) <0.001 2.67 (0.99–7.17) 0.052
AST (IU/L) 1.00 (0.97–1.03) 0.990 - 1.00 (0.98–1.01) 0.870 -
ALT(IU/L) 1.01 (0.99–1.03) 0.180 - 1.02 (1.00–1.03) 0.026 1.02 (0.99–1.04) 0.061
Fasting sugar (mg/dL) 1.01 (1.002–1.01) 0.002 1.00 (0.99–1.01) 0.22 1.01 (0.99–1.03) 0.259 -
HDL, male< 40, female < 50(mg/dL) 2.87 (1.71–4.81) <0.001 1.59 (0.88–2.86) 0.12 1.42 (0.61–3.31) 0.420 -
LDL(mg/dL) 0.99 (0.99–1.01) 0.850 - 1.00 (0.99–1.01) 0.846 -
Total cholesterol(mg/dL) 1.00 (0.99–1.01) 0.310 - 1.00 (0.99–1.01) 0.478 -
Triglyceride >150(mg/dL) 3.24 (1.97–5.33) <0.001 1.74 (0.98–3.08) 0.06 2.25 (1.02–4.97) 0.044 1.12 (0.37–3.42) 0.839
Platelet(1000/μL) 0.95 (0.55–1.64) 0.870 - 0.17 (0.06–0.48) 0.001 0.25 (0.06–0.99) 0.050
LSM (kPa) 0.95 (0.89–1.02) 0.180 - 0.93 (0.90–0.97) <0.001 0.94 (0.88–0.99) 0.027

BMI, body mass index; DM, diabetes mellitus; ALT, alanine aminotransferase; AST, aspartate aminotransferase; HDL, High-density lipoprotein; CAP, Controlled Attenuation Parameter; LSM, liver stiffness measurement; LDL, low-density lipoprotein