Table 5. Association of WWOX genotypic frequencies with HCC laboratory status.
| Characteristic | α-Fetoprotein a (ng/mL) | AST a(IU/L) | ALT a(IU/L) | AST/ALT ratio a |
|---|---|---|---|---|
| rs11545028 | ||||
| CC | 5119.4 ± 1411.9 | 156.8 ± 23.3 | 134.4 ± 18.4 | 1.55 ± 0.12 |
| CT+TT | 799.5 ± 229.9 | 101.1 ± 14.4 | 84.6 ± 11.1 | 1.36 ± 0.07 |
| p value | 0.013* | 0.072 | 0.041* | 0.232 |
| rs12918952 | ||||
| GG | 3785.0 ± 975.8 | 136.5 ± 16.9 | 116.5 ± 13.5 | 1.46 ± 0.08 |
| GA+AA | 579.4 ± 345.3 | 120.3 ± 25.3 | 99.6 ± 15.2 | 1.54 ± 0.23 |
| p value | 0.218 | 0.725 | 0.642 | 0.729 |
| rs3764340 | ||||
| CC | 3655.0 ± 991.4 | 99.9 ± 8.5 | 93.9 ± 8.5 | 1.40 ± 0.06 |
| CG+GG | 2170.3 ± 1520.9 | 291.0 ± 71.7 | 290.96 ± 71.7 | 1.78 ± 0.31 |
| p value | 0.506 | <0.001* | <0.001* | 0.059 |
| rs73569323 | ||||
| CC | 3443.6 ± 871.7 | 135.5 ± 15.4 | 115.1 ± 12.1 | 1.48 ± 0.08 |
| CT+TT | 78.1 ± 37.1 | 70.7 ± 25.6 | 72.7 ± 29.1 | 1.08 ± 0.11 |
| p value | 0.613 | 0.581 | 0.647 | 0.507 |
| rs383362 | ||||
| GG | 3317.0 ± 931.6 | 138.8 ± 18.6 | 116.8 ± 14.5 | 1.53 ± 0.10 |
| GT+TT | 3659.3 ± 2122.9 | 117.3 ± 16.2 | 105.1 ± 15.0 | 1.24 ± 0.06 |
| p value | 0.873 | 0.569 | 0.695 | 0.124 |
Mann-Whitney U test was used between two groups.
a Mean ± S.E.
* p value < 0.05 as statistically significant.