Table 3. Multivariate logistic regression with death at 90 days.
Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|
Odds ratio (CI 95%) | p-value | Odds ratio (CI 95%) | p-value | |
Positive daily fluid balancea (yes vs no) | 4.37 (2.15–8.88) | <0.001 | 4.55 (2.75–13.1) | <0.001 |
Infection | 1.97 (1.09–3.60) | 0.025 | ||
COPD | 2.32 (0.91–6.70) | 0.093 | 3.44 (1.14–10.4) | 0.028 |
Hematologic malignancy | 2.82 (1.13–8.06) | 0.035 | 5.14 (1.66–15.95) | 0.005 |
Hepatic cirrhosis | 2.47 (1.15–5.69) | 0.025 | 2.39 (0.99–5.78) | 0.052 |
Liver transplantation | 0.41 (0.19–0.88) | 0.023 | ||
Vasopressors | 2.12 (0.98–4.73) | 0.060 | ||
Mechanical ventilation | 2.89 (1.39–6.18) | 0.005 | ||
Sedation | 2.25 (1.15–4.46) | 0.018 | ||
Oliguria | 1.85 (1.26–2.71) | 0.002 | 2.36 (1.15–4.90) | 0.020 |
SAPS 3 score | 1.03 (1.01–1.05) | 0.002 | ||
Time from ICU admission to CVVHDF initiation (d) | 1.07 (0.99–1.18) | 0.093 | 1.10 (0.99–1.23) | 0.063 |
SOFA | 1.30 (1.15–1.46) | <0.001 | 1.27 (1.12–1.45) | <0.001 |
a Treatment-effects estimation by propensity-score matching
COPD, chronic obstructive pulmonary disease; CVVHDF, continuous venovenoushemodiafiltration; SAPS 3, Simplified Acute Physiology Score 3