Table 2. Correlations between pre-ART levels of HIV-1, inflammation, T cell activation and cycling and on-ART levels of HIV-1, inflammation, T cell activation and cycling.
Spearman correlation (p-value) with pre-ART level | 1 year on ART | 4 years on ART | 6–15 years on ART |
---|---|---|---|
HIV-1 DNA | 0.81 (<0.001) | 0.61 (<0.001) | 0.65 (<0.001) |
CA-RNA | 0.50 (<0.001) | 0.45 (<0.001) | 0.34 (0.017) |
IL-6 | 0.41 (<0.001) | 0.41 (<0.001) | 0.39 (0.001) |
hs-CRP | 0.33 (<0.001) | 0.48 (<0.001) | 0.30 (0.015) |
sCD14 | 0.40 (<0.001) | 0.47 (<0.001) | 0.45 (<0.001) |
sCD163 | 0.53 (<0.001) | 0.55 (<0.001) | 0.58 (<0.001) |
%CD38+HLA-DR+ (CD4 cells) | 0.45 (<0.001) | 0.23 (0.024) | 0.18 (0.17) |
%CD38+HLA-DR+ (CD8 cells) | 0.33 (<0.001) | 0.11 (0.29) | 0.14 (0.27) |
%Ki67 on CD4+ T-cells | 0.45 (<0.001) | 0.42 (<0.001) | 0.38 (0.002) |
%Ki67 on CD8+ T cells | 0.49 (<0.001) | 0.30 (0.003) | 0.40 (0.001) |