TABLE 3.
Slope index of inequalitya for 5-year change in aortic pulse wave velocity: sequential adjustment
Change in pulse wave velocity (per 5 years) | |||
SES indicators | Model adjustments | Increase (95% CI) | P value |
Father's social class | Base + lifestyle-related risk factorsb | 0.23 (−0.09, 0.55) | 0.16 |
Base + cardiovascular indicatorsc | 0.14 (−0.18, 0.45) | 0.39 | |
Base + all | 0.16 (−0.16, 0.49) | 0.33 | |
Employment grade | Base + lifestyle-related risk factorsb | 0.46 (0.20, 0.72) | 0.0006 |
Base + cardiovascular indicatorsc | 0.42 (0.17, 0.68) | 0.0012 | |
Base + all | 0.38 (0.11, 0.65) | 0.005 | |
Household income | Base + lifestyle-related risk factorsb | 0.66 (0.40, 0.92) | <0.001 |
Base + cardiovascular indicatorsc | 0.59 (0.34, 0.85) | <0.001 | |
Base + all | 0.58 (0.32, 0.85) | <0.001 | |
Education | Base + lifestyle-related risk factorsb | 0.35 (0.07, 0.63) | 0.016 |
Base + cardiovascular indicatorsc | 0.29 (0.013, 0.56) | 0.04 | |
Base + all | 0.30 (0.01, 0.58) | 0.04 |
aSlope index of inequality comparing the lowest SES with the highest SES. Base model is adjusted for age, sex, ethnic group, and mean arterial pressure at the time of the pulse wave velocity measurement.
bLifestyle-related risk factors are BMI, smoking, and alcohol intake.
cCardiovascular indicators are SBP, heart rate, total cholesterol, HDL cholesterol, diabetes, and antihypertensive use.
HDL, high-density lipoprotein; SES, socioeconomic status.