Figure. Local Control (LC), Locoregional Control (LRC), and Overall Survival (OS) Among 36 Patients Positive for and 141 Patients Negative for Lymphovascular Space Invasion (LVSI).
A, Local control, defined as the time from diagnosis to failure at the primary site or time to last follow-up, was analyzed among the patients who had pathological presence of LVSI (36 patients) and compared with those who did not (141 patients). Kaplan-Meier estimates for LC among these patients showed that 3-year LC is significantly worse with LVSI (54.9%) vs no LVSI (87.0%) (P < .01). B, Locoregional control, defined as the time from diagnosist to failure at primary site or in the neck or time to last follow-up, was analyzed among the patients who had pathological presence of LVSI (36 patients) and compared with those who did not (141 patients). Kaplan-Meier estimates for LRC among these patients showed that 3-year LRC is significantly worse with LVSI (38.8%) vs no LVSI (81.9%) (P < .01). C, Overall survival, defined as the time to death or time to last follow-up from diagnosis, was analyzed among the patients who had pathological presence of LVSI (36 patients) and compared with those who did not (141 patients). Kaplan-Meier estimates for OS among these patients showed that 3-yearOS is significantly worse with LVSI (53.2%) vs no LVSI (83.8%) (P = .02). Plus sign indicates censored data.