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. Author manuscript; available in PMC: 2017 Apr 20.
Published in final edited form as: JAMA Otolaryngol Head Neck Surg. 2017 Apr 1;143(4):382–388. doi: 10.1001/jamaoto.2016.3795

Table 4.

Multivariable Analysisa of Patient, Tumor, and Treatment Characteristics and Their Association With Overall Survival

Covariate Overall Survivalb
Hazard Ratio (95% CI) P Value
Age at diagnosis, y
 >44 4.38 (1.34–14.27) .01
 ≤44 1 [Reference]
Lymphovascular space invasion
 Positive 2.20 (1.19–4.06) .01
 Negative 1 [Reference]
Depth of invasion
 ≥3 mm 2.11 (0.99–4.51) .054
 <3 mm 1 [Reference]
Use of elective neck dissection
 Yes 0.64 (0.34–1.19) .16
 No 1 [Reference]
a

Backward selection with an a level of removal of .20 was used. The following variables were removed from the model: histological grade, margins, perineural invasion, race, sex, adjuvant therapy, and T-stage.

b

The reference group indicates no survival.