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. Author manuscript; available in PMC: 2017 Apr 20.
Published in final edited form as: J Phys Chem B. 2016 Oct 28;121(15):3352–3363. doi: 10.1021/acs.jpcb.6b08409

Figure 3.

Figure 3

2D-PMF with respect to the N-terminal linker flexibility and αC-helix rotation. All free energies are in the unit of kcal/mol, and all distances are in the unit of Å. (a) assembled SH2/SH3, and (b) re-assembled SH2/SH3.