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Progress of four electrostatic interactions during the transition, a subset of the electrostatic network identified by Ozkirimli et al. (a) Glu310:CD to Arg409:CZ (d1), (b) Glu310:CD to Lys295:NZ (d2), (c) Asp386:CG to Tyr416:OH, and (d) Arg385:CZ to Tyr416:OH.
