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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Addict Biol. 2016 Oct 20;22(6):1856–1869. doi: 10.1111/adb.12464

Figure 1. Excessive alcohol-drinking model.

Figure 1

Rats and mice experienced 7–8 weeks of intermittent access to 20% alcohol two-bottle choice drinking paradigm (IA20%-2BC). Control animals had access to water (W) only. Brain regions were removed after a short period of access to alcohol (Binge, 30 min after the last drinking session in rats, 4 hrs in mice) or after a withdrawal period of 24 hrs after the end of the last drinking session (Withdrawal).