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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Oral Dis. 2016 Dec 27;23(7):854–865. doi: 10.1111/odi.12598

Figure 3. IL-17 is critical for oral mucosal integrity and immunosurveillance.

Figure 3

Th17 cells, largely through its effector cytokine IL-17 (but also through IL-22), have an important role in maintaining mucosal barrier integrity. Key functions in IL-17-mediated mucosal surveillance are (1) regulation of epithelial tight junction protein expression (2), induction of antimicrobial peptide production (3) and release of neutrophil chemo-attractants.