Table 1.

Score sheet to assess sepsis-induced behaviour changes

Rat grimace scale				Clinical scoring*
Orbital tightening	0□	1□	2□	Reduced activity	0□	1□	2□
Nose/cheek flattening	0□	1□	2□	Sunken flanks	0□	1□	2□
Ear changes	0□	1□	2□	Back arching	0□	1□	2□
Whisker changes	0□	1□	2□	Piloerection	0□	1□	2□
				Bloated abdomen	0□	1□	2□
				Chromodacryorrhea (= eye discharge)	0□	1□	2□

Legend: The score sheet was adapted from [17] and www.ahwla.org.uk. *Six or more points in the clinical scoring lead to a preterm abortion of the experiment by injection of 1 ml phenobarbital i.v.