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. 2016 Oct 7;91(5):2079–2092. doi: 10.1007/s00204-016-1865-x

Fig. 4.

Fig. 4

Phase I metabolite production of mephenytoin (a), midazolam (b), phenacetin (c), bufuralol (d), bupropion (e), and diclofenac (f) during 5 days by hPCLS incubated in WME (red line), RegeneMed® (green dotted line), and Cellartis® (blue dashed line). Date are expressed as relative values ± SEM to the value at 0–3 h incubation. 3 (WME and Cellartis®) or 2 (RegeneMed®) donor livers were used for each study, using three hPCLS for each group in every experiment (color figure online)