Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
CYP51 in sterol biosynthesis. A, C. albicans CYP51 substrate lanosterol. B, products of the pathway in animals (cholesterol) and in fungi (ergosterol). C, three-step reaction of sterol 14α-demethylation. Each step involves one cycle of monooxygenation. 14α-Demethylation of lanosterol produces 4,4′-dimethylcholesta-8,14,24-triene-3β-ol (14α-desmethyllanosterol in Fig. 5).
