Table 1. Fractional Anisotropy for Tracts Connecting Subregions of the Striatum with the Frontal Cortex Regions.

		CO (n=32)	SZO (n=27)	P-value
Nucleus accumbens–DLPFC	R	0.34±0.02	0.36±0.02	0.0004a
	L	0.33±0.02	0.35±0.02	0.002a
Nucleus accumbens–mOFC	R	0.21±0.01	0.21±0.01	0.19
	L	0.19±0.01	0.19±0.01	0.19
Nucleus accumbens–IFG	R	0.33±0.01	0.34±0.02	0.02
	L	0.29±0.02	0.30±0.01	0.17
Caudate nucleus–DLPFC	R	0.33±0.01	0.34±0.01	0.02
	L	0.33±0.02	0.34±0.02	0.08
Caudate nucleus–mOFC	R	0.29±0.01	0.29±0.01	0.88
	L	0.27±0.01	0.27±0.01	0.48
Caudate nucleus–IFG	R	0.30±0.02	0.31±0.01	0.14
	L	0.33±0.02	0.33±0.01	0.28
Putamen–DLPFC	R	0.36±0.02	0.37±0.01	0.004
	L	0.37±0.02	0.38±0.01	0.04
Putamen–mOFC	R	0.29±0.01	0.29±0.01	0.06
	L	0.27±0.02	0.28±0.01	0.11
Putamen–IFG	R	0.27±0.01	0.28±0.01	0.01
	L	0.27±0.02	0.27±0.01	0.13

Abbreviations: CO, control adolescents; DLPFC, dorsolateral prefrontal cortex; IFG, inferior frontal gyrus; L, left; mOFC, medial orbital frontal cortex; R, right; SZO, schizophrenia offspring.

Values represent mean±S.D.

^aP-values survived Bonferroni correction for multiple testing.