Table 2. Mean Metabolite and rCBF for Younger and Older Adults with Schizophrenia and Age-Matched Controls.
Younger schizophrenia |
Younger controls |
Older schizophrenia |
Older controls |
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Mean±Std. Dev. (I.U.) | Mean CRLB (%) | Mean±Std. Dev. (I.U.) | Mean CRLB (%) | Mean±Std. Dev. (I.U.) | Mean CRLB (%) | Mean±Std. Dev. (I.U.) | Mean CRLB (%) | |
tNAA | 10.1±0.7 | 2.5 | 10.3±0.6 | 2.3 | 9.33±0.9 | 3.1 | 9.87±0.7 | 3.3 |
Gln | 2.34±0.5 | 16.3 | 2.19±0.4 | 17.1 | 2.57 ±1.0 | 17.3 | 2.39±0.5 | 17.4 |
Glu | 9.25±0.8 | 4.6 | 9.54±0.7 | 4.4 | 8.16±1.0 | 5.5 | 8.71±0.8 | 5.2 |
Glx | 11.49±1.1 | 5.1 | 11.7±1.0 | 4.8 | 10.6±1.4 | 5.8 | 11.0±1.1 | 5.5 |
tCr | 9.12±0.8 | 2.6 | 9.19±0.6 | 2.4 | 9.02±0.9 | 2.8 | 9.49±0.8 | 3.2 |
tCho | 1.83±0.3 | 4.9 | 1.82±0.3 | 4.5 | 1.93±0.3 | 5 | 1.89±0.3 | 4.7 |
mI | 6.60±0.7 | 3.9 | 6.72±0.5 | 3.4 | 6.82±0.9 | 4 | 7.00±0.8 | 3.8 |
GSH | 2.17±0.2 | 7.7 | 2.16±0.2 | 7.4 | 2.07±0.3 | 8.6 | 2.18±0.3 | 8.1 |
Gln/Glu | 0.25±0.06 | 0.23±0.04 | 0.30±0.09 | 0.27±0.06 | ||||
AC GM rCBF (ml/100g/min) | 55.7±13.9 | 58.8±10.5 | 54.1±14.2 | 54.2±9.8 | ||||
AC WM rCBF (ml/100g/min) | 55.7±13.9 | 58.8±10.5 | 54.1±14.2 | 54.2±9.8 | ||||
Whole Brain CBF (ml/100g/min) | 15.8±5.6 | 16.9±4.9 | 12.5±4.9 | 15.0±3.6 |