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Patient outcome based on the presence of proteinuria before and after sirolimus (SRL) initiation. a Renal outcome, b Survival outcome. B-A-, patients without proteinuria before (B-) and after (A-) SRL initiation; B + A-, patients with proteinuria before (B+) but not after (A-) SRL initiation; B-A+, patients without proteinuria (B-) but with new onset proteinuria after (A+) SRL initiation; and B + A+, patients with persistent proteinuria before (B+) and after (A+) SRL initiation
