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. 2017 Apr 20;15:83. doi: 10.1186/s12916-017-0852-2

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Discordance between direct ultracentrifugation measured and Friedewald-estimated LDL-C. Levels of LDLd-C (vertical axis) and LDLf-C (horizontal axis) are presented on this logarithmically scaled color density plot, with increasing density from light blue to purple. Panel a : Overall population; Panel b : TG < 150 mg/dL; Panel c : TG 150–199 mg/dL; Panel d : TG 200–399 mg/dL. A line of unity is included as well as lines indicating LDL-C 70 mg/dL. LDLd-C: directly-measured LDL-C by ultracentrifugation; LDLf-C: Friedewald-estimated LDL-C