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. 2017 Apr 20;36:57. doi: 10.1186/s13046-017-0517-1

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — VDR, RXR and PPARγ are significantly up-regulated in BRCA1 mutated breast cancer tissue. VDR, RXR and PPARγ immunoreactivity of sporadic vs. BRCA1 mutated breast cancer tissue was compared. All the three receptors were found to be significantly up-regulated in a BRCA1 mutated genetic background. P-values derived from relevant Mann–Whitney-U tests are shown