Table 1. Inflammatory gene expression, ΔC_t values and fold change relative to Sham-vehicle.

Gene	S-v	S-CN-105	TBI-v	TBI-CN-105	S-CN-105/S-v	TBI-v/S-v	TBI-CN-105/S-v
Cxcl3	3.0E − 05	2.3E − 05	6.7E − 01	1.6E + 00	0.8	22171.7	54032.0
Ccl11	7.8E − 05	2.5E − 04	6.4E − 01	1.8E − 01	3.2	8199.7	2253.1
Ccr4	3.9E − 06	6.0E − 06	2.6E − 02	3.1E − 02	1.5	6537.5	7945.9
Ccl20	2.6E − 05	1.1E − 04	1.2E − 01	7.9E − 02	4.4	4574.0	3086.8
Tlr6	4.7E − 04	6.2E − 04	1.2E + 00	7.0E − 03	1.3	2528.8	14.9
Ccl24	3.2E − 05	9.7E − 05	7.6E − 02	5.1E − 03	3.0	2356.9	159.1
Myd88	7.8E − 04	1.1E − 03	1.8E + 00	6.6E − 03	1.5	2327.8	8.5
Cxcl9	6.8E − 05	1.0E − 04	1.5E − 01	2.2E − 03	1.5	2265.1	32.2
Lta	1.2E − 04	2.6E − 04	1.3E − 01	1.1E − 01	2.3	1133.5	917.0
Tnfsf14	2.5E − 05	1.3E − 04	2.5E − 02	9.0E − 03	5.2	1027.7	365.9
Il9	1.2E − 05	*	1.2E − 02	1.4E − 02	**	957.7	1155.5
Ifng	7.3E − 05	5.8E − 05	5.6E − 02	4.3E − 03	0.8	767.1	59.7
Il10	1.9E − 05	1.1E − 04	1.5E − 02	1.6E − 03	5.7	766.1	82.2
Il1b	1.1E − 03	2.0E − 03	7.5E − 01	4.6E − 01	1.8	683.8	416.6
Il8rb	8.3E − 06	6.1E − 05	5.2E − 03	5.4E − 03	7.3	623.4	658.4
Il6	1.4E − 04	1.1E − 04	5.4E − 02	1.8E − 03	−1.3	395.1	13.2
Il1a	1.4E − 03	1.9E − 03	5.5E − 01	5.4E − 02	1.4	382.3	37.7
Cd40	5.4E − 04	8.3E − 04	1.6E − 01	2.1E − 02	1.5	301.4	38.8
Ccr2	2.6E − 04	5.5E − 04	7.1E − 02	1.5E − 03	2.1	271.6	5.6
Cxcl1	6.0E − 05	1.6E − 04	1.5E − 02	1.8E − 03	2.7	244.8	29.4
Ccr7	1.2E − 04	2.1E − 04	2.7E − 02	3.4E − 02	1.8	228.3	283.2
Il18rap	1.1E − 04	4.5E − 05	2.4E − 02	6.6E − 03	0.4	211.3	58.6
Tnf	2.8E − 05	3.5E − 05	5.5E − 03	3.8E − 02	1.3	197.3	1367.7
C4b	3.6E − 03	7.0E − 03	6.3E − 01	5.9E − 01	2.0	176.5	163.3
Il8ra	1.3E − 05	*	2.2E − 03	2.6E − 03	**	168.5	196.8
Cxcr4	4.3E − 03	6.6E − 03	6.6E − 01	9.0E − 02	1.5	153.8	21.0
Cxcl11	2.4E − 05	9.0E − 05	3.4E − 03	8.8E − 03	3.8	141.3	372.3
Il6ra	3.4E − 03	4.9E − 03	4.8E − 01	1.6E − 01	1.5	140.3	47.9
Il22	4.3E − 05	4.7E − 04	5.6E − 03	3.4E − 03	10.8	129.4	77.8
Il1rn	2.3E − 05	*	2.8E − 03	1.7E − 03	**	121.0	74.2
Ccl2	5.8E − 04	8.3E − 04	6.5E − 02	2.5E − 02	1.4	110.8	42.3
C3ar1	3.5E − 03	4.1E − 03	3.7E − 01	1.2E − 01	1.2	108.2	34.9
Il1f10	1.6E − 05	*	1.5E − 03	5.5E − 03	**	93.4	352.3
Ccl4	3.7E − 04	3.8E − 04	3.0E − 02	1.2E − 02	1.0	83.4	32.3
Tlr4	3.1E − 03	3.5E − 03	1.8E − 01	2.0E − 02	1.1	59.2	6.5
Il23a	2.7E − 05	8.0E − 05	1.2E − 03	2.3E − 02	3.0	45.4	838.4
Ripk2	7.0E − 03	1.1E − 02	2.3E − 01	2.1E − 01	1.5	32.0	30.1
Tlr7	1.7E − 03	2.6E − 03	4.8E − 02	9.1E − 01	1.6	28.7	546.2
Cxcl10	9.2E − 04	1.9E − 03	2.5E − 02	5.3E − 04	2.1	27.6	−1.7
Tlr1	4.8E − 04	1.0E − 03	1.1E − 02	7.4E − 03	2.2	22.0	15.4
Tirap	3.8E − 03	7.8E − 03	7.9E − 02	5.3E − 02	2.1	21.0	14.0
Ltb	5.1E − 04	1.0E − 03	1.1E − 02	3.9E − 02	2.0	20.9	75.7
Ccl25	5.6E − 03	1.4E − 02	1.1E − 01	9.5E − 02	2.6	20.3	16.9
Hdac4	6.0E − 02	9.1E − 02	9.0E − 01	8.3E − 01	1.5	14.9	13.9
Itgb2	5.5E − 03	1.3E − 02	8.1E − 02	5.3E − 02	2.5	14.7	9.6
Ccr3	1.7E − 03	2.1E − 03	2.1E − 02	1.1E − 01	1.2	12.3	66.6
Ccl3	5.1E − 04	8.0E − 04	6.1E − 03	8.9E − 03	1.6	12.0	17.7
Il7	1.1E − 04	3.2E − 04	1.1E − 03	5.9E − 01	3.1	10.8	5569.8
Tlr2	9.1E − 04	1.3E − 03	9.0E − 03	9.1E − 03	1.4	9.9	10.0
Fasl	2.1E − 04	1.9E − 04	1.3E − 03	6.7E − 04	0.9	6.3	3.2
Ccl5	8.9E − 04	1.1E − 03	5.5E − 03	3.4E − 03	1.2	6.2	3.8
Cxcl2	6.6E − 05	2.8E − 04	3.5E − 04	1.7E − 03	4.2	5.3	25.5
Nfkb1	1.7E − 02	3.1E − 02	8.8E − 02	5.3E − 03	1.8	5.3	−3.1
Cebpb	6.8E − 02	1.1E − 01	3.5E − 01	2.4E − 01	1.6	5.2	3.5
Ccl7	1.3E − 03	1.6E − 03	4.4E − 03	3.7E − 03	1.3	3.5	2.9
C3	4.1E − 04	7.0E − 04	1.3E − 03	1.9E − 03	1.7	3.1	4.6
Tlr3	1.5E − 02	2.3E − 02	4.5E − 02	5.8E − 02	1.6	3.0	3.9
Ccl22	1.2E − 04	3.8E − 04	3.6E − 04	2.2E − 02	3.1	2.9	176.2
Csf1	1.1E − 02	1.9E − 02	2.4E − 02	1.2E − 02	1.7	2.3	1.1
Fos	1.5E − 01	2.3E − 01	1.9E − 01	1.7E − 01	1.6	1.3	1.1
Tlr5	6.8E − 04	6.3E − 04	6.6E − 04	1.7E − 03	0.9	1.0	2.5
Il23r	1.1E − 04	1.5E − 04	1.4E − 04	8.0E − 04	1.4	−0.8	7.2
Tollip	1.6E − 01	3.2E − 01	1.5E − 01	5.1E − 02	1.9	−1.1	−3.2
Ccl19	1.9E − 02	2.9E − 02	1.7E − 02	3.4E − 03	1.5	−1.1	−5.8
Ccl17	2.6E − 03	4.2E − 03	1.7E − 03	1.0E − 03	1.6	−1.5	−2.6
Il10rb	1.5E − 02	3.0E − 02	8.4E − 03	2.2E − 02	2.0	−1.8	1.5
Flt3l	2.0E − 03	3.0E − 03	9.6E − 04	7.1E − 04	1.5	−2.1	−2.8
Ly96	3.8E − 03	7.2E − 03	1.2E − 03	7.7E − 02	1.9	−3.1	19.9
Il22ra2	2.4E − 05	1.1E − 04	7.5E − 06	8.2E − 02	4.8	−3.2	3448.3
Ccl8	7.5E − 04	2.1E − 03	1.3E − 04	4.2E − 03	2.8	−5.6	5.6
Ccr1	7.5E − 04	7.1E − 04	1.3E − 04	3.0E − 04	−1.1	−5.8	−2.5
Cxcl5	1.4E − 03	2.5E − 03	2.2E − 04	1.4E + 00	1.7	−6.5	957.4
Il1rap	3.1E − 02	4.4E − 02	1.8E − 03	8.2E − 04	1.5	−17.1	−37.5
Ccl12	3.6E − 03	6.5E − 03	2.1E − 04	1.3E − 02	1.8	−17.3	3.7
Il1r1	4.6E − 03	1.2E − 02	2.2E − 04	7.5E − 04	2.6	−21.5	−6.2
Nfatc3	8.7E − 03	2.1E − 02	3.2E − 04	3.2E + 00	2.4	−27.5	364.7
Il18	9.1E − 02	1.8E − 01	1.3E − 03	9.6E − 03	2.0	−68.6	−9.5
Bcl6	5.1E − 02	6.6E − 02	6.2E − 04	5.7E − 01	1.3	−82.1	11.2
Nr3c1	2.1E − 01	4.0E − 01	8.5E − 04	1.2E − 02	2.0	−243.3	−17.8
Ccl1	*	2.3E − 05	6.3E − 01	9.1E − 01	**	**	**
Cd40lg	*	6.9E − 05	4.9E − 03	4.2E − 03	**	**	**
Crp	*	*	5.9E − 04	7.1E − 04	**	**	**
Kng1	*	1.4E − 05	9.2E − 03	8.5E − 03	**	**	**
Nos2	8.8E − 05	8.9E − 05	*	1.6E − 01	1.0	**	1779.4

Inflammatory gene expression 24 hours post sham or TBI injury. Data is organized by fold change of TBI-vehicle normalized to sham-vehicle.

*Indicate mRNA expression was below the level of detection.

**Indicate relative value could not be calculated because one of the components was below the level of detection.