TABLE 2.
Patients with biochemical evidence of disease and negative surgical histology at reoperation (RO)
| Patient | Surgical indication | Largest target lesion1 | RO (n)/total RO (n) | Comment and target lesion follow-up | Eventual BCR |
|---|---|---|---|---|---|
| 1 | Palpation | 10 mm | 1/2 | Target resected; 0/1+ LNs | No |
| 4 | US FNA+ (twice) | 8 × 8 mm | 2/2 | 0/6+ LNs resected; F/U US confirmed unresected target; repeat US FNA− | No |
| 19 | Palpation | 10 mm | 2/4 | Target resected 0/1+ LNs; prior US considered the target benign | No |
| 22 | FDG-PET | SUV 4.5 | 1/2 | LNs with sinus histiocytosis; 0/22+ LNs | No |
| 25 | US FNA+ | 10 × 4 × 7 mm | 2/2 | Unstimulated Tg dropped from 2.2 to <0.5 postoperatively despite 0/13+ LNs; target not seen on F/U US | No |
| 29 | US FNA+ | 11 × 8 mm | 1/1 | 0/3+ LNs resected; no F/U US | No |
| 59 | US | 6 × 5 mm | 2/2 | FNA deferred because target was surrounded by vascular structures; 0/5+ LNs; target not seen on F/U US | No |
| 62 | US FNA+ | 6 × 6 mm | 2/2 | Surgery stopped because dense adhesions prohibited safe dissection; F/U US confirmed unresected target | No |
| 85 | US | 8 × 7 mm | 1/1 | No F/U US | No |
| 91 | US | 18 × 12 mm, subclavicular mass | 2/3 | Tumor not found by thoroscopy; repeat US+; third RO resected 2/3+ LNs | No |
F/U, Follow-up; LN, lymph nodes.
1
US dimensions are width × depth in transverse view or craniocaudal length × depth × width.