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Tan IIA suppresses expression of inflammatory cytokines in serum of ApoE–/– mice. ApoE−/− mice at 6 weeks were gavaged with Tan IIA (30 mg/kg) for 20 weeks and then sacrificed. (A-D) The concentrations of IL-1β, IL-6, MCP-1, and TNF-α in serum of ApoE–/– mice treated with Tan IIA were significantly decreased by ELISA assay. n=8, *P<0.05, error bars indicate that data were expressed as the mean±s.d.
