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Effects of AuNPs on autophagy. PDLPs were treated with AuNPs (5, 13 and 45 nm) at concentration of 10 μM. (A) Real-time PCR analysis of LC3 and Beclin1 mRNA expression on day 1 and 3. (B) Western blot analysis of LC3-II and p62 expression on day 3. *p<0.05, **p<0.01.