Table 1.
Venous blood glucose and plasma insulin concentrations before (0 min) and during (60–240 min) the morning infusion period
| Parameter and groups | 0 min | 60 min | 120 min | 180 min | 240 min |
|---|---|---|---|---|---|
| Blood glucose (mg/dL) | |||||
| SAL + SALno-clamp | 87 ± 1 | 87 ± 2 | 86 ± 2 | 83 ± 1† | 84 ± 2 |
| GLC + GLCno-clamp | 87 ± 3 | 122 ± 5*† | 111 ± 6*† | 108 ± 6*† | 107 ± 11*† |
| Plasma insulin (µU/mL) | |||||
| SAL + SALno-clamp | 9 ± 1 | 7 ± 1 | 9 ± 2 | 7 ± 1 | 8 ± 1 |
| GLC + GLCno-clamp | 7 ± 2 | 47 ± 24*† | 26 ± 1*† | 11 ± 1*† | 21 ± 3*† |
Data are mean ± SEM. SAL + SALno-clamp includes six dogs that underwent the clamp (SAL) and three dogs from which tissue was harvested before the clamp (SALno-clamp). GLC + GLCno-clamp includes six dogs that underwent the clamp (GLC) and three dogs from which tissue was harvested before the clamp (GLCno-clamp).
*P < 0.05 vs. SAL + SALno-clamp;
†P < 0.05- vs. 0-min sample in the same group.